CD226 anticorps (APC)

N° du produit ABIN7672811

Cet anticorps Rat Monoclonal détecte spécifiquement CD226 dans FACS. Il présente une réactivité envers Souris.

Aperçu rapide pour CD226 anticorps (APC) (ABIN7672811)

Antigène: CD226

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp CD226 est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Clone: 10E5

Détail du produit anti-CD226 anticorps (APC)

Fonction: APC Anti-Mouse CD226 Antibody

Purification: 0

Pureté: 0

Isotype: IgG2b, kappa

Information d'application

Indications d'application: Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0. 1 % sodium azide, 1 % BSA, pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: 4 °C

Stockage commentaire: 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur CD226

Antigène: CD226

Autre désignation: CD226

Sujet:

Synonyms: DNAM-1|PTA1(platelet and T cell activation antigen 1)|TLISA1|LFA-1 associated Molecule PTA-1

Background: CD226 (DNAM-1) is constitutively expressed on native CD8+ cells and on CD4+ T cells, macrophages and NK cells.This antibody (10E5) was reported to bind about 40 % of inactivated CD4+ cells and binds only to differentiated Th1 cells, but not to Th2 or Th0 cells.It is also reported to suppress antigen-specific T cell expansion and EAE (experimental allergic encephalitis) mediated by Th1 cells.

Poids moléculaire: 0

ID gène: 225825

UniProt: Q8K4F0

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints